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Anti-PAK2 Polyclonal Antibody
Cat: K008213P
Summary:
【Product name】:Anti-PAK2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5062 【Swiss Prot】:Q13177
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human PAK2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.?
Verified picture:
Western blot analysis with PAK2 antibody diluted at 1:500; Lane:Jurkat,NIH3T3,Mouse thyroid
Immunohistochemistry of paraffin-embedded Human thyroid cancer with PAK2 antibody diluted at 1:50