Anti-CDH3 Polyclonal Antibody
Cat: K008218P
Summary:
| 【Product name】：Anti-CDH3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1001 | 【Swiss Prot】：P22223 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1: 50-200 | |
| 【Immunogen】：Recombinant protein of human CDH3 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Verified picture:
Western blot analysis with CDH3 antibody diluted at 1:400;Lane:MCF7,HUVEC,HepG2,293T,K562
Immunohistochemistry of paraffin-embedded Human tonsil using CDH3 antibody diluted at 1:80