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Anti-PTP4A2 Polyclonal Antibody - SAlexa Fluor 594
Cat: K008224P - SAlexa Fluor 594
Summary:
【Product name】:Anti-PTP4A2 Polyclonal Antibody - SAlexa Fluor 594 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:8073 【Swiss Prot】:Q12974
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human PTP4A2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.
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