下载
Anti-ALDH8A1 Polyclonal Antibody
Cat: K008294P
Summary:
【Product name】:Anti-ALDH8A1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:64577 【Swiss Prot】:Q9H2A2
【Species reactivity】:Rat,Mouse,Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human ALDH8A1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.
Verified picture:
Western blot analysis with ALDH8A1 antibody diluted at 1:2500; Lane: Mouse liver , Mouse kidney
Immunohistochemistry of paraffin-embedded Rat brain with ALDH8A1 antibody diluted at 1:30