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Anti-ATG4D Polyclonal Antibody - SAlexa Fluor 555
Cat: K008329P - SAlexa Fluor 555
Summary:
【Product name】:Anti-ATG4D Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:84971 【Swiss Prot】:Q86TL0
【Species reactivity】:Human,Mouse
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human ATG4D
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes.
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