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Anti-HK1/HK2 Polyclonal Antibody
Cat: K008343P
Summary:
【Product name】:Anti-HK1/HK2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3098/3099 【Swiss Prot】:P19367/P52789
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human HK1/HK2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.
Verified picture:
Western blot analysis with HK1/HK2 antibody diluted at 1:2500; Lane: A431,K-562, MAD-ME-231,Hela,HepG2,MCF7,Jurkat
Immunohistochemistry of paraffin-embedded Human lung cancer with HK1/HK2 antibody diluted at 1:50