Anti-TRIP4 Polyclonal Antibody
Cat: K008355P
Summary:
| 【Product name】：Anti-TRIP4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9325 | 【Swiss Prot】：Q15650 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human TRIP4 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Activating signal co-integrator-1 (ASC-1), originally identified as TRIP4, is a transcriptional co-activator of nuclear receptors that associates with specific components of the RNA polymerase II complex and binds the basal transcription factors TBP and TFIIA. ASC-1 functions with the transcription integrators SRC-1 and CBP/p300 through its zinc finger motif and is dependent on their ligand-dependent transactivation domain, AF2. Endogenous ASC-1 in HeLa cells is predominantly a nuclear protein. Under conditions of serum starvation, ASC-1 localizes to the cytoplasm.?
Verified picture:
Western blot analysis with TRIP4 antibody diluted at 1:1000; Lane: A431,Hela,293T,NIH3T3
Immunohistochemistry of paraffin-embedded Human lung cancer with TRIP4 antibody diluted at 1:50