Anti-ICAM1 Polyclonal Antibody - Cy3
Cat: K008365P - Cy3
Summary:
| 【Product name】：Anti-ICAM1 Polyclonal Antibody - Cy3 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3383 | 【Swiss Prot】：P05362 |
| 【Species reactivity】：Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human ICAM1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
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