下载
Anti-BMP2 Polyclonal Antibody - RBITC
Cat: K101544P - RBITC
Summary:
【Product name】:Anti-BMP2 Polyclonal Antibody - RBITC 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:12156 【Swiss Prot】:P21274
【Species reactivity】:Mouse
【Tested applications】:WB ELISA IHC ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of mouse BMP2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.
Verified picture: