Anti-SOX2 Polyclonal Antibody - SAlexa Fluor 647
Cat: K101546P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-SOX2 Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6657 | 【Swiss Prot】：P48431 |
| 【Species reactivity】：Mouse | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human SOX2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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