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Anti-CADH2 Polyclonal Antibody - SAlexa Fluor 594
Cat: K106417P - SAlexa Fluor 594
Summary:
【Product name】:Anti-CADH2 Polyclonal Antibody - SAlexa Fluor 594 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1000 【Swiss Prot】:P19022
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human CADH2
【Public Immunogen Range】:375-425/906aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).
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