Anti-IASPP Polyclonal Antibody - HRP
Cat: K106447P - HRP
Summary:
| 【Product name】：Anti-IASPP Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：10848 | 【Swiss Prot】：Q8WUF5 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human IASPP | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
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