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Anti-IASPP Polyclonal Antibody - Cy3.5
Cat: K106447P - Cy3.5
Summary:
【Product name】:Anti-IASPP Polyclonal Antibody - Cy3.5 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:10848 【Swiss Prot】:Q8WUF5
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB
【Immunogen】:A synthetic peptide of human IASPP
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
Verified picture: