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Anti-Delta4 Polyclonal Antibody - SAlexa Fluor 568
Cat: K106504P - SAlexa Fluor 568
Summary:
【Product name】:Anti-Delta4 Polyclonal Antibody - SAlexa Fluor 568 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:54567 【Swiss Prot】:Q9NR61
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB
【Immunogen】:A synthetic peptide of human Delta4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.
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