Anti-PDGF-B Polyclonal Antibody
Cat: K106535P
Summary:
| 【Product name】：Anti-PDGF-B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5155 | 【Swiss Prot】：P01127 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human PDGFB | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family.
Verified picture:
Immunohistochemistry of paraffin-embedded Skin cancer(hu) using PDGF-B at dilution of 1:100 (x100 lens,x200 lens).