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Anti-EGFR Polyclonal Antibody
Cat: K106563P
Summary:
【Product name】:Anti-EGFR Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1956 【Swiss Prot】:P00533
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC,WB,IP,IF
【Immunogen】:A synthetic peptide of human EGFR
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Verified picture:
Western blot analysis with EGFR antibody diluted at 1:3000;Lane:Hela,HepG2.
Immunohistochemistry of paraffin-embedded Lung cancer(hu) using EGFR at dilution of 1:100 (x100 lens,x200 lens).
Immunoprecipitation analysis of 1mg Hela extracts using EGFR antibody(IP:1:200;WB:1:2000).Control IgG: Normal Rabbit IgG.