Anti-GAD65 Polyclonal Antibody
Cat: K106572P
Summary:
| 【Product name】：Anti-GAD65 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2572 | 【Swiss Prot】：Q05329 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB,IHC | |
| 【Immunogen】：A synthetic peptide of human GAD65 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Verified picture:
Western blot analysis with GAD65 antibody at dilution at 1:1000
Immunohistochemistry of paraffin-embedded Skin cancer(hu) using GAD65 at dilution of 1:100 (x100 lens,x200 lens).