Anti-SQSTM1 Polyclonal Antibody - HRP
Cat: K106574P - HRP
Summary:
| 【Product name】：Anti-SQSTM1 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：8878 | 【Swiss Prot】：Q13501 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human SQSTM1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
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