Anti-TLR4 Polyclonal Antibody
Cat: K106584P
Summary:
| 【Product name】：Anti-TLR4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7099 | 【Swiss Prot】：O00206 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of human TLR4 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific.
Verified picture:
Western blot analysis with TLR4 antibody at dilution at 1:1000