Anti-NR3C2 Polyclonal Antibody - Cy5.5
Cat: K106612P - Cy5.5
Summary:
| 【Product name】：Anti-NR3C2 Polyclonal Antibody - Cy5.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4306 | 【Swiss Prot】：P08235 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human NR3C2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
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