Anti-RhoA Polyclonal Antibody
Cat: K106637P
Summary:
| 【Product name】：Anti-RhoA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：387 | 【Swiss Prot】：P61586 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human RhoA | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Verified picture:
Immunohistochemistry of paraffin-embedded Pancreatic cancer(hu) using RhoA at dilution of 1:50 (x100 lens,x200 lens).
Immunohistochemistry of paraffin-embedded Prostate cancer(hu) using RhoA at dilution of 1:50 (x100 lens,x200 lens).