Anti-Smad4 Polyclonal Antibody - HRP
Cat: K106653P - HRP
Summary:
| 【Product name】：Anti-Smad4 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4089 | 【Swiss Prot】：Q13485 |
| 【Species reactivity】：Mouse | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Smad4 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8.
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