Anti-SPAST Polyclonal Antibody
Cat: K106676P
Summary:
| 【Product name】：Anti-SPAST Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6683 | 【Swiss Prot】：Q9UBP0 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human Spastin | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated.Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold . Severing activity is not dependent on tubulin acetylation or detyrosination.
Verified picture:
Western blot analysis with SPAST antibody at dilution at 1:1000
Immunohistochemistry of paraffin-embedded Ovarian cancer(hu) using Spastin at dilution of 1:100 (x100 lens,x200 lens).