Anti-CASP8 Polyclonal Antibody
Cat: K106679P
Summary:
| 【Product name】：Anti-CASP8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：841 | 【Swiss Prot】：Q14790 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB,IHC | |
| 【Immunogen】：A synthetic peptide of human CASP8 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli.
Verified picture:
Western blot analysis with CASP8 antibody at dilution at 1:1000
Immunohistochemistry of paraffin-embedded Skin cancer(hu) using CASP8 at dilution of 1:100 (x100 lens,x200 lens).