Anti-Klotho Polyclonal Antibody - HRP
Cat: K106698P - HRP
Summary:
| 【Product name】：Anti-Klotho Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9365 | 【Swiss Prot】：Q9UEF7 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Klotho | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).
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