Anti-IRAK4 Polyclonal Antibody - RBITC
Cat: K106734P - RBITC
Summary:
| 【Product name】：Anti-IRAK4 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：51135 | 【Swiss Prot】：Q9NWZ3 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human IRAK4 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.
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