下载
Anti-IRAK4 Polyclonal Antibody - Cy3.5
Cat: K106734P - Cy3.5
Summary:
【Product name】:Anti-IRAK4 Polyclonal Antibody - Cy3.5 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:51135 【Swiss Prot】:Q9NWZ3
【Species reactivity】:Human
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human IRAK4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.
Verified picture: