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Anti-AKR1C3 Polyclonal Antibody - SAlexa Fluor 488
Cat: K106744P - SAlexa Fluor 488
Summary:
【Product name】:Anti-AKR1C3 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:8644 【Swiss Prot】:P42330
【Species reactivity】:Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human AKR1C3
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
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