Anti-APRT Polyclonal Antibody
Cat: K106746P
Summary:
| 【Product name】：Anti-APRT Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：353 | 【Swiss Prot】：P07741 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of human APRT | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene
Verified picture:
Western blot analysis with APRT antibody at dilution at 1:1000