Anti-IL-4R Polyclonal Antibody
Cat: K106750P
Summary:
| 【Product name】：Anti-IL-4R Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3566 | 【Swiss Prot】：P24394 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human IL-4R | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Verified picture:
Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using IL-4R at dilution of 1:50 (x100 lens,x200 lens).