Anti-MDK Polyclonal Antibody
Cat: K106782P
Summary:
| 【Product name】：Anti-MDK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4192 | 【Swiss Prot】：P21741 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human MDK | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation.
Verified picture:
Western blot analysis with Midkine antibody at dilution at 1:1000
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using Midkine at dilution of 1:50 (x100 lens,x200 lens).