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Anti-GNAS Polyclonal Antibody - FITC
Cat: K106913P - FITC
Summary:
【Product name】:Anti-GNAS Polyclonal Antibody - FITC 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:2778 【Swiss Prot】:P63092
【Species reactivity】:Human
【Tested applications】:ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human GNAS
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.
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