Anti-TNFSF18 Polyclonal Antibody
Cat: K106930P
Summary:
| 【Product name】：Anti-TNFSF18 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：8995 | 【Swiss Prot】：Q9UNG2 |
| 【Species reactivity】：Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of human TNFSF18 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).
Verified picture:
Western blot analysis with TNFSF18 antibody diluted at 1:10000;Lane: Mouse skeletal muscle.