Anti-TRAF6 Polyclonal Antibody
Cat: K106938P
Summary:
| 【Product name】：Anti-TRAF6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7189 | 【Swiss Prot】：Q9Y4K3 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human TRAF6 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN.
Verified picture:
Immunohistochemistry of paraffin-embedded Human renal cancer with TRAF6 antibody diluted at 1:50.