Anti-TNFAIP1 Polyclonal Antibody
Cat: K107019P
Summary:
| 【Product name】：Anti-TNFAIP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7126 | 【Swiss Prot】：Q13829 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human TNFAIP1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Verified picture:
Immunohistochemistry of paraffin-embedded Human lung cancer with TNFAIP1 antibody diluted at 1:20.