Anti-CYP46A1 Polyclonal Antibody
Cat: K107031P
Summary:
| 【Product name】：Anti-CYP46A1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10858 | 【Swiss Prot】：Q9Y6A2 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human CYP46A1 | |
| 【Public Immunogen Range】：380-430/500aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
Verified picture:
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with CYP46A1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human cervical cancer with CYP46A1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human lung cancer with CYP46A1 antibody diluted at 1:100.