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Anti-SMPD1 Polyclonal Antibody
Cat: K107041P
Summary:
【Product name】:Anti-SMPD1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6609 【Swiss Prot】:P17405
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human SMPD1
【Public Immunogen Range】:550-600/631aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Verified picture:
Immunohistochemistry of paraffin-embedded Human endometrial cancer with SMPD1 antibody diluted at 1:100.