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Anti-LRP6 Polyclonal Antibody
Cat: K107054P
Summary:
【Product name】:Anti-LRP6 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:4040 【Swiss Prot】:O75581
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:3000-5000. IHC 1:50-200.
【Immunogen】:A synthetic peptide of human LRP6
【Public Immunogen Range】:1540-1590/1613aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.
Verified picture:
Western blot analysis with LRP6 antibody diluted at 1:1000;Lane: Mouse liver.
Immunohistochemistry of paraffin-embedded Human testis cancer with LRP6 antibody diluted at 1:100.