Anti-TERF1 Polyclonal Antibody - RBITC
Cat: K107057P - RBITC
Summary:
| 【Product name】：Anti-TERF1 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7013 | 【Swiss Prot】：P54274 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human TERF1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
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