Anti-BCL2 Monoclonal Antibody
Cat: K200018M
Summary:
| 【Product name】：Anti-BCL2 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Affinity purification |
| 【Gene ID】：596 | 【Swiss Prot】：P10415 |
| 【Tested applications】：IF,WB,IP | |
| 【Recommended dilution】：WB 1:1000-2000. IF 1:100-200. IP 1:50-500. | |
| 【Immunogen】：A synthetic peptide coupled to KLH | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
Verified picture:
Western blot analysis with BCL2 antibody diluted at 1:2000;Lane: HeLa.
Immunofluorescence analysis of Hela cells using BCL2 antibody diluted at 1:100.