下载
Anti-BCL2 Monoclonal Antibody - SAlexa Fluor 405
Cat: K200018M - SAlexa Fluor 405
Summary:
【Product name】:Anti-BCL2 Monoclonal Antibody - SAlexa Fluor 405 【Source】:Mouse
【Isotype】:IgG1
【Gene ID】:596 【Swiss Prot】:P10415
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IF,WB
【Immunogen】:A synthetic peptide coupled to KLH
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
Verified picture: