Anti-EGFR Monoclonal Antibody - SAlexa Fluor 488
Cat: K200028M - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-EGFR Monoclonal Antibody - SAlexa Fluor 488 | 【Source】：Mouse |
| 【Isotype】：IgG1 | |
| 【Gene ID】：1956 | 【Swiss Prot】：P00533 |
| 【Species reactivity】：Human | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide coupled to KLH | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.
Verified picture: