Anti-FasLG Polyclonal Antibody
Cat: K001613P
Summary:
| 【Product name】：Anti-FasLG Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：356 | 【Swiss Prot】：P48023 |
| 【Species reactivity】：Mouse,Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human FasLG | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
Verified picture:
Immunohistochemistry of paraffin-embedded Human esophageal cancer with FasLG antibody diluted at 1:100.