Anti-OTC Polyclonal Antibody - SAlexa Fluor 488
Cat: K107189P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-OTC Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5009 | 【Swiss Prot】：P00480 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human OTC | |
| 【Public Immunogen Range】：270-320/354aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
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