Anti-SDHA Polyclonal Antibody
Cat: K107190P
Summary:
| 【Product name】：Anti-SDHA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：66945 | 【Swiss Prot】：Q8K2B3 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of mouse SDHA | |
| 【Public Immunogen Range】：590-640/664aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with SDHA antibody diluted at 1:6000;Lane: HepG2,NIH3T3,MCF7,Mouse stomach,Mouse liver,Rat heart.
Immunohistochemistry of paraffin-embedded Human liver cancer with SDHA antibody diluted at 1:200.