Anti-Serca2 Polyclonal Antibody
Cat: K107217P
Summary:
| 【Product name】：Anti-Serca2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：11938 | 【Swiss Prot】：O55143 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of mouse Serca2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Sarcoplasmic/endoplasmic reticulum Calcium-ATPase 2 (SERCA2) is a magnesium-dependent pump that catalyzes the hydrolysis of ATP and translocates calcium from the cytosol to the sarcoplasmic reticulum lumen. There are 2 SERCA2 isoforms that differ in the 3' UTR. The SERCA2A isoform is highly expressed in heart and slow twitch skeletal muscle and is important to the regulation of the contraction and relaxation cycle, while the SERCA2B isoform is expressed in smooth muscle and adult epidermis. SERCA2 is also known as ATP2A2, ATP2B, DAR, DD, and MGC45367.
Verified picture:
Western blot analysis with Serca2 antibody diluted at 1:6000;Lane: HeLa,293T.
Immunohistochemistry of paraffin-embedded Human cervical cancer with Serca2 antibody diluted at 1:100.