Anti-JTB Polyclonal Antibody - SAlexa Fluor 680
Cat: K107221P - SAlexa Fluor 680
Summary:
| 【Product name】：Anti-JTB Polyclonal Antibody - SAlexa Fluor 680 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10899 | 【Swiss Prot】：O76095 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human JTB | |
| 【Public Immunogen Range】：65-115/146aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
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