Anti-SIGLEC5 Polyclonal Antibody
Cat: K008394P
Summary:
| 【Product name】：Anti-SIGLEC5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：8778 | 【Swiss Prot】：O15389 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human SIGLEC5 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion
Verified picture:
Western blot analysis with SIGLEC5 antibody diluted at 1:500;Lane: Mouse liver,Mouse lung,Mouse spleen
Immunohistochemistry of paraffin-embedded Human colorectal cancer with SIGLEC5 antibody diluted at 1:30