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Anti-SIGLEC5 Polyclonal Antibody - SAlexa Fluor 640
Cat: K008394P - SAlexa Fluor 640
Summary:
【Product name】:Anti-SIGLEC5 Polyclonal Antibody - SAlexa Fluor 640 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:8778 【Swiss Prot】:O15389
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:200-1000. IHC 1:10-100.
【Immunogen】:Recombinant protein of human SIGLEC5
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion
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