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Anti-SEPT7 Polyclonal Antibody
Cat: K008400P
Summary:
【Product name】:Anti-SEPT7 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:989 【Swiss Prot】:Q16181
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human SEPT7
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19
Verified picture:
Western blot analysis with SEPT7 antibody diluted at 1:1000;Lane: Hela,293T,Jurkat,NIH3T3,Mouse brain,Rat brain
Immunohistochemistry of paraffin-embedded Human colorectal cancer with SEPT7 antibody diluted at 1:60